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Category:Audio software
Category:Digital audio editorsSix week follow-up study of an L-rhamnose controlled feeding trial in healthy subjects.
Treatment of healthy subjects with 1.5 g of L-rhamnose/d for 6 wk was evaluated by two trial courses in a controlled manner. In the first trial, 8 subjects (40% female) received 4 capsules/d, each containing 900 mg of L-rhamnose, and 1 capsule/d containing 300 mg of sucrose, and they were compared to a group of 8 subjects (63% female) who received 1 capsule/d of the same carbohydrate mixture in their normal diet. In the second trial, 7 subjects (36% female) received 1 capsule/d of L-rhamnose and the remaining 8 subjects (50% female) received 1 capsule/d of sucrose. The results of both trials were similar. Blood samples were taken daily, urine was collected daily, and oral examinations were carried out once weekly. Serum samples and oral fluids were tested for antibody responses to typhoid vaccines. Vomiting occurred in 20% of subjects during the L-rhamnose trial but was not observed in the sucrose trial. There was a statistically significant increase in IgG titer against both Ty21a and Vi polysaccharide antigens. No differences in serum antibody titers to Vi and Ty21a antigens were found between the sucrose and L-rhamnose trials. Serum samples from the L-rhamnose trial were also tested for antibodies against Salmonella choleraesuis, S. paratyphi B, and S. paratyphi A. Only a slight increase in titers was found against S. paratyphi B. ac619d1d87
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